Empoli - Sassuolo
- The only two previous meetings between Empoli and Sassuolo were won 3-1 by the home side last season.
- Previously, these sides had met 10 times in Serie B: Empoli won the first two, before picking up only three points in the ensuing seven, as result of three draws.
- Empoli are one of the three sides (alongside Verona and AC Milan) to have always conceded goals in this campaign.
- Sassuolo are the only side still unbeaten in this competition - an unbeaten run that stretches to 11 games, taking into account also the end of last season (7 wins).
- Sassuolo have 12 points after the first six match-days - over their first two Serie A campaigns they had collected only two (13/14) and three (14/15) points after the same number of games.
- Empoli have won only two of their last five home games, while Sassuolo have taken 13 of the last 15 available away from home.
- Empoli have already conceded a league-high five headed goals, while Sassuolo are yet to concede their first goal with a header so far in this competition.
- Sassuolo have already used 18 Italian players in this campaign - more than any other side.
- Domenico Berardi has failed to score in his last four league appearances - his longest drought in Serie A since January.
- Daniele Croce has scored his only Serie A goal to date against Sassuolo, in the last Serie A campaign.
Fiorentina - Atalanta
- Fiorentina have won their last six league games against Atalanta, keeping a clean sheet in four of those.
- The Viola are unbeaten in their last 14 home games against Atalanta, whose last win at the Franchi was in January 1993.
- Fiorentina have won 10 of their last 11 Serie A fixtures, losing one 3-1 against Torino.
- In fact, the Tuscans have won their last six home games, without conceding a goal in the last five.
- Fiorentina have collected the most points in Serie A since start of 2015 (55 in 28 games).
- Atalanta have won their last two league games against Empoli and Sampdoria. The last time they won three in a row was in March 2014.
- Fiorentina have conceded only 13 shots on target (and only 51 in total) to their opponents - fewer than any other side since the start of this campaign.
- Atalanta have trailed only in the injury time against Inter so far in this Serie A.
- Nikola Kalinic has scored four goals in his last two league appearances, from a total of only five shots on target.
- Both Kalinic and Ilicic have found the target with eight of their nine total shots so far (89%) - the highest ratio amongst players with six or more shots attempted.
- Mauricio Pinilla has scored four goals over his last five games against Fiorentina in the league, but none in the two played last season.
Juventus - Bologna
- Juventus have won their last four Serie A games against Bologna, keeping a clean sheet in the last three.
- The Bianconeri have lost only one of their last 25 league games against Bologna (W16).
- Before losing 1-0 in their last trip to the Juventus Stadium, Bologna had found the net in their previous nine visits to Juve's ground in the league.
- Juventus have lost three of their first six games of the season - something that hadn't happened to the Old Lady in Serie A since 1987/88.
- Juve have just one win in seven Serie A games for the first time since March 2012, but on that occasion they had remained unbeaten (W1 D6).
- Juventus are winless in their last three home games - this is the first time they've failed to win three home games in a row in Serie A since playing at the Juventus Stadium.
- Bologna have lost the most games so far in this Serie A campaign (five).
- Bologna are one of the two teams (alongside Genoa) yet to pick up their first point away from home this season.
- Bologna are the only side yet to score a goal after the break, while Juventus have scored the fewest before half-time (one).
- Paul Pogba is the only player of this Serie A to have hit the woodwork twice.
- Amongst current Serie A strikers who have already scored at least one goal in the top-flight, Robet Acquafresca is the one who hasn't found the net for the longest time (38).
Lazio - Frosinone
- Lazio have won each of the three home games played so far in this campaign, scoring two goals in each match.
- The Biancocelesti haven't conceded at home for 227 minutes, since Mancosu's goal for Bologna on match-day 1.
- Lazio have scored in each of their last 11 home games (25 goals in the process).
- Lazio have won their last two league games - last time they won three in a row was in April.
- For the first time in their Serie A history (last Thursday against Empoli), Frosinone managed to win a Serie A game, to score more than a single goal and to keep a clean sheet in the top-flight.
- Frosinone have conceded in each of their last five games on the road between this and last season (seven in total).
- Lazio have already conceded four goals from outside the box in this Serie A - more than any other side.
- Frosinone have picked up 21 yellow cards so far - a league-high.
- Lucas Biglia has scored two goals in two Serie A appearances so far this term, last season he scored three in his 27 total appearances in the league.
- Modibo Diakité made his Serie A when he was playing for Lazio - he scored two goals in 65 league appearances for the Biancocelesti between 2007 and 2012.
AC Milan - Napoli
- Napoli have won only one of their last 21 games at AC Milan's ground (2-1 in September 2013), with the Rossoneri having the better 11 times in the process.
- However, Napoli have won three of their last four league games against AC Milan, losing the last one at the San Siro, back in December.
- AC Milan have nine points after the first six match-days, last season under Inzaghi they had 11 after the same number of games.
- The Rossoneri have conceded in 12 of their last 13 league games (22 in total).
- Napoli have scored in 14 of their last 15 games, failing to find the net only against Carpi.
- Napoli's last away win in the league came back in April (3-0 against Cagliari), with three losses and three draws away from the San Paolo since then.
- Napoli are yet to concede their first goal from outside the box in this competition.
- AC Milan have already conceded four goals in the opening 15 minutes of play - more than any other side in this Serie A.
- Pepe Reina has saved only one penalty so far in his Serie A career, against Mario Balotelli in September 2013.
- Gonzalo Higuain has scored four goals in his four previous appearances against AC Milan - only against Lazio he has netted more in Serie A.
- Jack Bonaventura scored his first Serie A goal right against Napoli, in April 2012 - he also scored a goal for AC Milan against the Partenopei last season.
Palermo - Roma
- Roma's last Serie A win against Palermo was in November 2012 - since then the Rosanero have won two and drawn one.
- Over their last seven meetings at Palermo's ground, the same result never accrued twice in a row (last season it ended 1-1 at the Barbera).
- Roma have already scored with 10 different players - a record in this competition.
- Palermo are the only Serie A side this season that have conceded two own goals.
- After picking up seven points from the first three games of the season, Palermo have lost the ensuing three. The last time they lost four in a row was in May 2013, before being relegated to Serie B.
- Roma have scored in their last 17 league games (29 goals in the process).
- Roma lost their last away game against Sampdoria - the last time they lost two away games in a row in Serie A was in May 2014.
- If Palermo lose it will be their 400th loss in Serie A history.
- Alberto Gilardino has already scored 10 goals in Serie A against Roma, only against Chievo (11) and Udinese (15) he has bagged more in the top-flight.
- Miralem Pjanic has already scored nine goals from a direct free-kick in Serie A since 2011 - the Bosnian midfielder has found the back of the net every 7.2 free-kicks taken so far in Italy.
Sampdoria - Inter
- Before winning 1-0 back in March, Sampdoria hadn't beaten Inter for eight consecutive games in Serie A (D3 L5).
- Their last draw at the Ferraris came in August 2008 - since then, Inter lead by three wins to two.
- The Bluicerchiati have managed to score more than a single goal against Inter only twice over their last 17 meetings in the league.
- Inter have won five of their last six away games in Serie A, losing one at the Ferraris against Genoa in May.
- Inter's last two away defeats in Serie A came at this ground, one against Samp in March, and one against Genoa in May.
- Samp have won their three home games of the season, netting two or more goals on each occasion.
- Inter have used only two Italian players so far in this campaign, fewer than any other side (Santon and Ranocchia).
- Pedro Pereira is the youngest player with three appearances this season amongst Europe's top-five leagues.
- Luis Muriel has already scored three goals in seven Serie A appearances against Inter, only against Roma (four) he has netted more to date.
- Mauro Icardi has scored three goals in three games against his former side Sampdoria, including a brace at the Ferraris on the first meeting since joining Inter.
Udinese - Genoa
- Over the last 10 Serie A meetings between Udinese and Genoa the same has not been repeated twice in a row (last time they shared a 1-1 draw).
- Udinese have scored in 18 of their 21 previous games against Genoa at the Friuli, but failed to score in two of the last five.
- The Friulani have lost their last six home games in the league - they've never lost seven in a row so far in the top-flight.
- Udinese are the only side of this Serie A campaign yet to pick up points at home.
- However, Genoa have lost their last four games on the road, and have conceded in each of their last 11 away games.
- Genoa haven't drawn any of their last 16 league games.
- Udinese's last home draw was back in March against Fiorentina (2-2), since then they've won one and lost seven.
- Both Udinese and Genoa have scored just one goal before half-time so far - a joint-low in this competition.
- Sebastian De Maio scored the last of his three Serie A goals to date against Udinese in their last meeting back in April.
- Antonio Di Natale's last Serie A goal came back in May - since then he's gone seven games without scoring, which is his longest drought in the league since January 2014.
- However, Di Natale has found the net in each of his last three home games against Genoa in Serie A.